Instrumentation: Orbitrap Fusion Lumos MS with ETD

The newest addition to our  line of mass spectrometers, the Thermo Scientific™ Orbitrap Fusion™ Lumos Tribrid MS allows systems biology researchers to test new limits of quantitation and protein characterization. It incorporates the brightest ion source, a segmented quadrupole mass filter with improved selectivity and ion transmission, Advanced Vacuum Technology for improved ion transmission to the Orbitrap mass analyzer and higher-capacity ETD fragmentation. Combined, these hardware improvements enable the new tribrid instrument to excel in the most challenging applications, including analysis of low level PTMs, multiplexed relative quantitation using isobaric tags (TMT).

Supported By

The facility is supported by the NIH shared instrumentation grant numbers

S10 OD016234 (Synapt-HDX-MS) and  S10 OD021724 (LUMOS Orbi-Trap).

Please reference these grant numbers for publications resulting from data obtained from these instrumentations.

Funds from Moores Cancer Center of UC San Diego